(+)-ISOPINOCAMPHEOL Property

Melting point:

52-55 °C

Boiling point:

219 °C(lit.)

Density 

0.8389 (rough estimate)

refractive index 

1.4710 (estimate)

Flash point:

93 °C

pka

15.35±0.60(Predicted)

LogP

2.805 (est)

Safety

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

(+)-ISOPINOCAMPHEOL Chemical Properties,Usage,Production

Uses

(1S,2S,3S,5R)-(+)-Isopinocampheol may be used in the preparation of

• thermotropic chiral nematic side-chain copolymers
• ortho-(diphenylphosphino)phenylphosphonous acid di[(1S,2S,3S,5R)-2,6,6-trimethyl-bicyclo[3.1.1]-hept-3-yl]ester, a phosphino-phosphonite ligand
• O,O′bis[(1S,2S,3S,5R)2,6,6-trimethylbicyclo[3.1.1]hept-3-yl] dithiophosphoric acid, a bioactive compound with antifungal effect

General Description

(1S,2S,3S,5R)-(+)-Isopinocampheol is a chiral terpenol.

Purification Methods

Dissolve it in Et2O, dry over MgSO4, filter, evaporate, then recrystallise it from pet ether. Also recrystallise it from aqueous EtOH and distil it in a vacuum. [Kergomard & Geneix Bull Soc Chim Fr 394 1958, Zweifel & Brown J Am Chem Soc 86 393 1964.] The 3,4-dinitrobenzoyl derivative has m 100-101o, the phenylcarbamoyl derivative has m 137-138o and the acid -phthalate has m 125-126o. [Beilstein 6 III 282, 283.]